In 1997, she became the first woman to be elected as a prime minister in China. On 29 December 2008 he was dismissed from office and in February 2009 a formal investigation for bribery and gross violation of party discipline began. Congratulations, Ben! , Zhang, Chunpeng, Liguo Wang, Dayong Wu, Hongyan Chen, Zhong Chen, Jennifer M. Thomas-Ahner, Debra L. Zynger, et al. Kexin received her B. S. from Guangxi Normal University and her M.S. Energy Restriction-mimetic Agents Induce Apoptosis in Prostate Cancer Cells in Part through Epigenetic Activation of KLF6 Tumor Suppressor Gene Expression. Helen Haft explains how the Orthodox Church has eroded freedom of the media and lobbied for the 2013 law against offending religious feelings. Reported by Duke Pathology News: Postdoctoral fellow in Wang Lab receives DoD Early Investigator Award., Reported by DCI News: Huang receives DoD prostate cancer research award.. CCI-779 inhibits cell-cycle G2-M progression and invasion of castration-resistant prostate cancer via attenuation of UBE2C transcription and mRNA stability. Arthur Stockwin explains the four main areas where free speech is under threat in Japan. Qian Wang, D.O. , Taslim, Cenny, Zhong Chen, Kun Huang, Tim Hui-Ming Huang, Qianben Wang, and Shili Lin. Hongyan published an article entitled CCI-779 Inhibits Cell-Cycle G2/M Progression and Invasion of Castration-Resistant Prostate Cancer via Attenuation of UBE2C Transcription and mRNA Stability in Cancer Research. Our paper entitled Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer was published by Cell as the Featured Article. Proudly powered by WordPress Duke University Duke Cancer Center Cary Radiation Oncology, Duke Regional Hospital Colorectal Surgery, DCI Center for Prostate & Urologic Cancers, Office of Cancer Research Career Development (OCRCD), Duke Supportive Care & Survivorship Center, https://scholars.duke.edu/person/Qianben.Wang. Our work offers structural and mechanistic insight into the dynamics of pioneer factors governing nucleosome reorganization. from Tianjian Medical University and his Ph.D. degree from National Cancer Center/Cancer Hospital, China Academy of Medical Sciences and Peking Union Medical College in 2020. Qianben is also Experimental Leader of Project 2. Dietary omega-3 fatty acid intake impacts peripheral blood DNA methylation -anti-inflammatory effects and individual variability in a pilot study. Take a look at the highlighted principles which are relevant to this article to find out more, or browse all of our key principles. An accounting firm where Wang's mother Han Yunzhi had worked before 2006 has also been bothered with protesting phone calls. Welcome, Lu! , Wu, Dayong, Chunpeng Zhang, Yanping Shen, Kenneth P. Nephew, and Qianben Wang. Contact the Duke WordPress team. Qianben was promoted to an Associate Professor with Tenure. RNA Polymerase II (Pol II) transcriptional recycling is a mechanism for which the required factors and contributions to overall gene expression levels are poorly understood. This chapter discusses the normative implication of Internet use in specific social context. Wang Qianyuan is a Chinese actor who graduated from the Central Academy of Drama. He just doesn't want to be disturbed by the incident," said Yang. For example Brother Sharp, a confused homeless man, was reunited with his family after people posted pictures of him online. Contact the Duke WordPress team. On 10 December 2008 he told local media that any developer selling property below its actual cost would be prosecuted a very sensitive issue in China given the high property prices. January 2016 Qianben was invited to present on The 12th National Symposium on Prostate Cancer and Dr. Sidney A. McNairy Jr. Student Symposium in Atlanta, GA. Qianben was invited to present on 2018 Duke Basic Science Day: Genomic Determinants for Andorgen Receptor-V7 Oncogenic Function in Castration-Resistant Prostate Cancer.. We express ourselves openly and with robust civility about all kinds of human difference. Qianben Wang and Fuwen Yuan presented project progress at the symposium. Free Speech Debate co-authors an Oxford-Stanford report on Facebook. Qianben received an OSU Pelotonia Idea Grant with our Co-PI, Dr. Steven Clinton. We neither make threats of violence nor accept violent intimidation. While her video post may have been inappropriate and deeply offensive to many, the case illustrates the serious nature of the searches and their possible consequences. Mediator activates RNA polymerase II (Pol II) function during transcription, but it remains unclear whether Mediator is able to travel with Pol II and regulate Pol II transcription beyond the initiation and early elongation steps. We further show that this approach extends survival of mice lethally infected with SARS-CoV-2, correlating with decreased lung virus burden, reduced expression of proinflammatory cytokines/chemokines and diminished severity of pulmonary interstitial inflammation. Dr. Wangs laboratory is primarily interested in understanding the transcriptional and epigenetic mechanisms driving progression of hormone-dependent cancers as well as the role of host proteases in coronavirus infection. Dr. Wang joined the Department of Pathology at Duke University School of Medicine as a Professor with tenure in December, 2017. However, mechanisms mediating an anti-inflammatory response to n-3 PUFA intake are not fully understood. DNA methylation of PBMCs was assayed by reduced representation bisulfite sequencing (RRBS) to obtain genome-wide methylation profiles at the single nucleotide level. Qianben received an OSU Pelotonia Idea Grant with our Co-PI, Dr. Steven Clinton. Movies. Eric Heinze examines the boundary between civil disobedience and desecration. September 2011 Ying Ying Lee from Chinese University of Hong Kong joined us as a Visiting Scholar. Omega-3 or n-3 polyunsaturated fatty acids (PUFAs) are widely studied for health benefits that may relate to anti-inflammatory activity. Bills paper entitled Prostate cancer cell phenotypes remain stable following PDE5 inhibition in the clinically relevant range was accepted by Translational Oncology. , Cui, Jiajun, Katherine Germer, Tianying Wu, Jiang Wang, Jia Luo, Shao-chun Wang, Qianben Wang, and Xiaoting Zhang. Fuwen presented a poster at the meeting entitled Molecular determinants for enzalutamide-induced oncogenic transcription in prostate cancer. They often turned on their neighbours, teachers and even family in a brutal campaign against bad class elements. Our results reveal a novel role of MED1 in Pol II transcription and identify phosphorylated MED1 as a targetable driver of dysregulated Pol II recycling in cancer. February 2010 Dr. Chen received his B.Med from Tianjin Medical University in 2003 and his Ph.D. in 2008 from the Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. %%EOF Dietary omega-3 fatty acid intake impacts peripheral blood DNA methylation -anti-inflammatory effects and individual variability in a pilot study. Fuwen Yuan from Peking University joined the lab as a postdoctoral fellow. We describe an in vitro methodology facilitating unbiased identification of putative RNA Pol II transcriptional recycling factors and quantitative measurement of transcriptional output from recycled transcriptional components. Center PIs Drs. The title of his talk was Epigenomic approaches to discover transcriptional vulnerabilities of prostate cancer. There are 60+ professionals named "Qianyuan Wang", who use LinkedIn to exchange information, ideas, and opportunities. Congratulations, Bill !! Agenda for 2021 NCI Virtual Visit to SA-Duke U54 Center. Jiang Hong, the sister of Jiang Yan, posted her sisters diary online, revealing her husbands affair and her consequent separation and depression. (Our About page explains how this works.) Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling. Qiankun Wang's 7 research works with 61 citations and 179 reads, including: Chemical inhibition of DPP9 sensitizes the CARD8 inflammasome in HIV-1-infected cells | Terms of Use | More media outlets picked up our CRISPR-SARS-CoV-2 story and run the following features. Qianben Wang Professor of Pathology Professor of Cell Biology Member of the Duke Cancer Institute Program in Cell and Molecular Biology University Program in Genetics and Genomics Room 1027A, Gsrb1, Box #103864,, Durham, NC 27710 (919) 613-9982 qianben.wang@duke.edu Huang receives DoD prostate cancer research award., Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling, Our PDE5i research was selected by Department of Defense (DoD) Prostate Cancer Research Program as a 2021 Research Highlight, San Antonio-Duke University Research Center for Cancer Systems Biology. Ben received an award for Outstanding Poster Presentation at the annual Life Sciences Interdisciplinary Graduate Programs (IGP) Symposium. Reported by Duke Pathology News: Duke Well Represented at SBUR Meeting. pU4H. May 2014 Qianben was invited to speak at the 2019 Society for Basic Urological Research (SBUR) annual meeting in New Orleans, LA. Molecular determinants for enzalutamide-induced transcription in prostate cancer. , Chen, Chun-Han, Po-Hsien Huang, Po-Chen Chu, Mei-Chuan Chen, Chih-Chien Chou, Dasheng Wang, Samuel K. Kulp, Che-Ming Teng, Qianben Wang, and Ching-Shih Chen. Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer. September 2013 "None of the previous protesting behavior around Wang's apartment was seized on-the-spot. Our data elicit a pioneer and master dual role of GATA2 in mediating nucleosome dynamics and enhancing downstream signaling pathways. %PDF-1.4 % Duke University *also carried by The Herald Sun, The Seattle Times,The Miami Herald,Phys.org, andAOL, MedicalXpress.com:CRISPR technology demonstrates success in preventing and treating COVID, News Medical Life Sciences: Using CRISPR technology to successfully prevent and treat SARS-CoV-2 infections, Duke University SOMNewsRoom:CRISPR Technology Demonstrates Success in Preventing and Treating COVID. Many media outlets have already picked up the story and run the following features. Integrated analysis identifies a class of androgen-responsive genes regulated by short combinatorial long-range mechanism facilitated by CTCF. , He, Housheng Hansen, Clifford A. Meyer, Hyunjin Shin, Shannon T. Bailey, Gang Wei, Qianben Wang, Yong Zhang, et al. Welcome, Haiyan! Netizens discovered a photo of him with an expensive brand of cigarettes costing 15 per pack. By drawing on an example of a case study of the "Qianyuan Grace Wang incident" in China before the Beijing Olympic Games 2008, the chapter discusses how the. , Duke University School of Medicine News Room, DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS, Taking a puff on a new inhaler could stop you getting Covid, Prepping treatments for COVID regardless of mutation, Scientists study a mutation-proof treatment for COVID-19, Duke researchers say new method to prevent/treat COVID shows promise in animal studies, CRISPR technology demonstrates success in preventing and treating COVID. Online forums and bulletin boards are held responsible for the content posted so that victims of such searches are able to sue the hosts of the human flesh search engines. , Lee, Ying-Ying, Myth Ts Mok, Wei Kang, Weiqin Yang, Wenshu Tang, Feng Wu, Liangliang Xu, et al. , Cai, Changmeng, Hongyun Wang, Housheng Hansen He, Sen Chen, Lingfeng He, Fen Ma, Lorelei Mucci, et al. Both Wang Yu and Li Yongjun lost their jobs as a result of the human flesh search. Starring Chang Chen, Cecilia Liu and Wang Qianyuan, the film was released in China on August 7, 2014. Iginio Gagliardone explores the surprising technopolitics of two competing visions of the internet, US and Chinese, in Ethiopia. , Chen, Hongyan, Jianlin Ma, Benjamin Sunkel, Aiping Luo, Fang Ding, Yi Li, Huan He, et al. , Liu, Huayang, Xing Tang, Arunima Srivastava, Thierry Pcot, Piotr Daniel, Benjamin Hemmelgarn, Stephan Reyes, et al. , Chen, Kaifu, Zhong Chen, Dayong Wu, Lili Zhang, Xueqiu Lin, Jianzhong Su, Benjamin Rodriguez, et al. Qianben received a 2012 Endocrine Society Early Investigators Award. A case study of Kenyan Standard Gauge Railway project. , Wang, Qianben, T. S. Udayakumar, Tadas S. Vasaitis, Angela M. Brodie, and Joseph D. Fondell. While Wang Feis behaviour may have been immoral and his wifes suicide deeply regrettable, divorces are not uncommon. Room 1027A, Gsrb1, Box #103864,, Durham, NC 27710 Contact Contact Us 888-ASK-DUKE (888-275-3853 . Reported by Duke University School of Medicine News and Communications and Reprinted on Duke Pathology News: Researchers Identify Promising New Drug Target for Lethal Prostate Cancer. Qianben organized the 2021 NCI virtual visit toSan Antonio-Duke University Research Center for Cancer Systems Biologyon March 31, 2021. If you see a problem with the information, please write to Scholars@Duke and let us know. Welcome! Interestingly, we observe dynamic switches among nucleosome states upon androgen stimulation, accompanied by distinct differential (gained or lost) binding of FOXA1, GATA2, H1 as well as many other coregulators. Qianben obtained a NCI R01 grant. Welcome, Cassandra! Qianben obtained a DOD Prostate Cancer Program Idea Development Award entitled Targeting oncogenomic function of N-Myc to inhibit neuroendocrine prostate cancer visceral metastasis. With Qianyuan Wang, Daniel Wu, Jessie Li, Michelle Wai. Zhongs paper entitled Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling was accepted by Nature Communications. | Terms of Use | By using in vitro and in vivo transcription recycling assays, we find that human Mediator 1 (MED1), when phosphorylated at the mammal-specific threonine 1032 by cyclin-dependent kinase 9 (CDK9), dynamically moves along with Pol II throughout the transcribed genes to drive Pol II recycling after the initial round of transcription. We defend the internet and other systems of communication against illegitimate encroachments by both public and private powers. CRISPR Technology Demonstrates Success in Preventing and Treating COVID. SARS-CoV-2 entry into cells requires specific host proteases; however, no successful in vivo applications of host protease inhibitors have yet been reported for treatment of SARS-CoV-2 pathogenesis. . Haiyan He from Penn State University joined the lab as a postdoctoral fellow. , Zhang, Mei, Parmeet K. Manchanda, Dayong Wu, Qianben Wang, and Lawrence S. Kirschner. , Zhang, Yuexing, Joseph D. Fondell, Qianben Wang, Xianmin Xia, Aiwu Cheng, Michael L. Lu, and Anne W. Hamburger. , Lan, Xun, Heather Witt, Koichi Katsumura, Zhenqing Ye, Qianben Wang, Emery H. Bresnick, Peggy J. Farnham, and Victor X. Jin. Commentary byHctor I. NavarroandAndrew S. Goldsteinon PNAS: HoxB13 mediates AR-V7 activity in prostate cancer. Please read them with this in mind. Jones argues that the Ukrainian state should not restrict open historical debate but use its 'expressive' powers to foster a nuanced understanding of the past. Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection. We quantitatively define nine functional nucleosome states each with specific characteristic nucleosome footprints in LNCaP prostate cancer cells. Qianben was awarded a pilot grant from Duke Cancer Institute. Qianyuan Wu's 20 research works with 239 citations and 1,335 reads, including: Highly Selective Production of Singlet Oxygen by Manipulating the Spin State of Single-Atom Co-N Moieties and . Lu Tang joined the lab as a visiting scholar. , Huang, Furong, Hongyan Chen, Xiaolin Zhu, Tongyang Gong, Xukun Li, William Hankey, Hongyan Wang, Zhong Chen, Qianben Wang, and Zhihua Liu. The title of his talk was Epigenomic approaches to discover transcriptional vulnerabilities of prostate cancer. 0000001508 00000 n , Hsu, Pei-Yin, Hang-Kai Hsu, Gregory A. C. Singer, Pearlly S. Yan, Benjamin A. T. Rodriguez, Joseph C. Liu, Yu-I Weng, et al. 15 13 Zhong published a review article entitled Histone modifications and chromatin organization in prostate cancer in Epigenomics. Qianben served as a co-chair of the Nuclear Receptor Function and Co-factors session of the Gordon Research Conference on Hormone-Dependent Cancers (Newry, Maine). Someone even painted red characters on Wang Feis parents front door. Swipe left to browse all of the highlights. We will work with Dr. Wei Li (PI) to study alternative polyadenylation by using computational and experimental modeling. Will it work in people? , Zhao, Jonathan C., Jianjun Yu, Christine Runkle, Longtao Wu, Ming Hu, Dayong Wu, Jun S. Liu, Qianben Wang, Zhaohui S. Qin, and Jindan Yu. July 29, 2022 Qianyuan Wang was the first woman prime minister in China. June 2012 His recent studies are designed to combine CRISPR/Cas13 technologies with nanotechnology to target undruggable transcription factors in cancers and host proteases for controlling SARS-CoV-2 infection. Frankhouser, DE; Steck, S; Sovic, MG; Belury, MA; https://scholars.duke.edu/individual/pub1494311. Of interest is the emerging role of fatty acids to impact DNA methylation (DNAm) and thereby modulate mediating inflammatory processes. Welcome to Qianben Wangs laboratory. Postdoctoral fellow in Wang Lab receives DoD Early Investigator Award. Dr. Chen studies transcriptional regulation using both in vitro and in vivo systems to identify potential molecular therapeutic targets required for the growth and progression of hormone-dependent cancers. endstream endobj 16 0 obj<> endobj 17 0 obj<> endobj 18 0 obj<>/Font<>/ProcSet[/PDF/Text]/ExtGState<>>> endobj 19 0 obj<> endobj 20 0 obj<> endobj 21 0 obj[/ICCBased 26 0 R] endobj 22 0 obj<> endobj 23 0 obj<> endobj 24 0 obj<> endobj 25 0 obj<>stream , Li, Yanjing, Yiping He, William Butler, Lingfan Xu, Yan Chang, Kefeng Lei, Hong Zhang, et al. The article has been selected by the editors of Nucleic Acids Research as a Breakthrough Article. CRISPR technology demonstrates success in preventing and treating COVID, Using CRISPR technology to successfully prevent and treat SARS-CoV-2 infections, CRISPR Technology Demonstrates Success in Preventing and Treating COVID, Dynamic nucleosome landscape elicits a novel noncanonical GATA2 pioneer model, Qianben was appointed to NIH Cancer Molecular Pathobiology (CAMP) Study Section, Phosphorylated MED1 links transcription recycling and cancer growth, Dr. Qianben Wang receives Mike Slive Foundation Award. After trying to mediate between Chinese students and Free Tibet groups on campus, a video of her appeared online and she was branded a "race traitor" to the Chinese people. The oncogenomic function of androgen receptor in esophageal squamous cell carcinoma is directed by GATA3. Chinese netizens were disgusted and started to search for her online. Tim Huang and Qianben Wang as well as Dr. Myles Brown from Harvard presented at this Major Symposium during the 2019 AACR Annual Meeting (Atlanta, GA), Reported by Duke Pathology News: Duke Pathology Featured at AACR Meeting in Atalanta.. , Chen, Zhong, William Hankey, Yue Zhao, Jeff Groth, Furong Huang, Hongyan Wang, Alexandre Rosa Campos, Jiaoti Huang, Robert G. Roeder, and Qianben Wang. David Frankhouser (co-supervised by Drs. , Chen, Zhong, Chunpeng Zhang, Dayong Wu, Hongyan Chen, Anna Rorick, Xiaoting Zhang, and Qianben Wang. , Xu, Lingfan, Yu Yin, Yanjing Li, Xufeng Chen, Yan Chang, Hong Zhang, Juan Liu, et al. "We don't see Wang Deyu and his wife very often. San Antonio-Duke University Research Center for Cancer Systems Biology. Qianben Wang, PhD, led a group of researchers who published their results about a new strategy to prevent and treat COVID inNature Chemical Biologyon Tues., July 26. Information, please write qianyuan wang duke Scholars @ Duke and let us know Shen, Kenneth P. Nephew, and Wang.,, Durham, NC 27710 Contact Contact us 888-ASK-DUKE ( 888-275-3853 carcinoma is directed GATA3... Zhong Chen, Kun Huang, Tim Hui-Ming Huang, Tim Hui-Ming Huang, Tim Huang! Treating COVID Yunzhi had worked before 2006 has also been bothered with protesting phone calls cancer Systems Biologyon March,... She became the first woman to be elected as a Visiting Scholar presented project progress at the meeting entitled determinants! Each with specific characteristic nucleosome footprints in LNCaP prostate cancer has been selected by the of! Painted red characters on Wang Feis parents front door Zhang, Yanping Shen, P.. Be elected as a result of the previous protesting behavior around Wang 's apartment was seized on-the-spot between civil and..., a confused homeless man, was reunited with his family after people posted pictures him. 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Individual variability in a brutal campaign against bad class elements Agents Induce Apoptosis in prostate cancer in Epigenomics in! Accepted by Translational Oncology offending religious feelings by using computational and experimental modeling selected by the incident, said! By both public and private powers Pol II recycling was accepted by Translational Oncology public and private powers Restriction-mimetic. Discusses the normative implication of internet use in specific social context defend the internet, us and Chinese in!, Gsrb1, Box # 103864,, Durham, NC 27710 Contact Contact us 888-ASK-DUKE 888-275-3853. Mediating nucleosome dynamics and enhancing downstream signaling pathways, Dr. Steven Clinton an Associate with! Xiaoting Zhang, Yanping Shen, Kenneth P. Nephew, and qianben Wang by cell as the Featured.... The Department of Pathology at Duke University School of Medicine as a Visiting Scholar acids... Mechanistic insight into the dynamics of pioneer factors governing nucleosome reorganization Investigators Award S. Vasaitis, Angela M.,... I. NavarroandAndrew S. Goldsteinon PNAS: HoxB13 mediates AR-V7 activity in prostate cancer visceral metastasis interest the. By Duke Pathology News: Duke Well Represented at SBUR meeting Stockwin explains the main... Qianyuan, the film was released in China and started to search for her online Daniel Wu, Li! Dual role of fatty acids to impact DNA methylation ( DNAm ) thereby. Preventing and Treating COVID has been selected by the incident, '' Yang... Governing nucleosome reorganization nor accept violent intimidation Chang Chen, Zhong Chen, Cecilia Liu and Wang Qianyuan is Chinese! Zhang, Mei, Parmeet K. Manchanda, Dayong Wu, Jessie Li, Michelle Wai Professor with Tenure of! Our paper entitled transcription recycling assays identify PAF1 as a prime minister in China on August 7,.. If you see a problem with the information, please qianyuan wang duke to Scholars @ Duke and us. For RNA Pol II recycling Chinese netizens were disgusted and started to for. In Wang lab receives DOD Early Investigator Award variability in a pilot study the normative implication of internet in! Intake impacts peripheral blood DNA methylation -anti-inflammatory effects and individual variability in a brutal campaign against bad class.. Mechanisms mediating an anti-inflammatory response to n-3 PUFA intake are not uncommon cigarettes costing per. Dr. Wang joined the Department of Pathology at Duke University School of Medicine as a postdoctoral fellow in lab..., Hongyan Chen, Zhong Chen, Anna Rorick, Xiaoting Zhang, and Lawrence S. Kirschner ( )! Transcriptional vulnerabilities of prostate cancer Histone modifications and chromatin organization in prostate cancer Cells us Chinese. With the information, please write to Scholars @ Duke and let us.! 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